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Read More About Tadalafil
Marketed under the name Cialis, Tadalafil is amongst a new category of medicines which assist in the achievement and maintenance of an erection. Its recommended dose is 20mg.
Cialis is the only drug which is not only fast acting (works in 30 minutes) but is also know to be effective for as long as 36 hours, thus enabling you to choose the moment that is just right for you as well as your partner. You can take Cialis in the morning and be ready for the right moment during that day, evening or even during the next day. Millions of men have benefited from Cialis as it works effectively in mild, moderate or severe erectile dysfunction.

What should I know about tadalafil?

A handful os users have lost vision in one eye as a result of taking tadalafil. This loss of vision is known as non-arteritic anterior ischemic optic neuropathy (NAION). NAION causes a sudden loss of vision because there is a restricted flow of blood to the optic nerve. At this stage, it is not known if NAION is caused by tadalafil. NAION also afflicts those who have not been taking the drug. Patients at greater risk are those who have:
  • heart disease;
  • more than 50 years of age;
  • diabetes;
  • high blood pressure;
  • high cholesterol;
  • smoking-related conditions; or
  • certain eye problems.
Stop using tadalafil if you suffer any loss of vision and seek immediate medical advice.
Do not take the drug if you have been prescribed any of the following:
  • a nitrate such as nitroglycerin (Nitrostat, Nitrolingual, Nitro-Dur, Nitro-Bid, Minitran, Deponit, Transderm-Nitro, others), isosorbide dinitrate (Dilatrate-SR, Isordil, Sorbitrate), isosorbide mononitrate (Imdur, ISMO, Monoket), and others;
  • nitrates are also found in some recreational drugs such as amyl nitrate or nitrite ("poppers"); or
  • an alpha blocker (other than tamsulosin (Flomax) 0.4 mg once a day) such as doxazosin (Cardura), guanadrel (Hylorel), prazosin (Minipress), terazosin (Hytrin), alfuzosin (Uroxatral), and others.
Ingestion of tadalafil with any of the above medicines may cause very low blood pressure, and this can result in dizziness, fainting, stroke, or heart attack.
If you maintain an erection for more than four hours, seek emergency advice straight away. A prolonged erection can cause permanent harm to your penis. Do not engage in any more sex until the symptoms have gone and seek further medical advice if you experience (pain, tightness, discomfort, numbness, or tingling in the chest, arms, neck, or jaw) when having sex.
Tadalafil is generally taken when required before sex. Its effects can last 36 hours or longer. Take advice from your healthcare practitioner about how often to take the drug and follow that advice.

What does the drug do?

It relaxes the muscles within the penis. This allows more blood to pass into your penis, thereby allowing an erection to be achieved and sustained.
It is used to treat ED (erectile dysfunction).
It can also be used to treat other conditions.

What should I tell my doctor if I intend to take tadalafil?

A handful os users have lost vision in one eye as a result of taking tadalafil. This loss of vision is known as non-arteritic anterior ischemic optic neuropathy (NAION). NAION causes a sudden loss of vision because there is a restricted flow of blood to the optic nerve. At this stage, it is not known if NAION is caused by tadalafil. NAION also afflicts those who have not been taking the drug. Patients at greater risk are those who have:
  • heart disease;
  • more than 50 years of age;
  • diabetes;
  • high blood pressure;
  • high cholesterol;
  • smoking-related conditions; or
  • certain eye problems.
Stop using tadalafil if you suffer any loss of vision and seek immediate medical advice.
Do not take the drug if you have been prescribed any of the following:
  • a nitrate such as nitroglycerin (Nitrostat, Nitrolingual, Nitro-Dur, Nitro-Bid, Minitran, Deponit, Transderm-Nitro, others), isosorbide dinitrate (Dilatrate-SR, Isordil, Sorbitrate), isosorbide mononitrate (Imdur, ISMO, Monoket), and others;
  • nitrates are also found in some recreational drugs such as amyl nitrate or nitrite ("poppers"); or
  • an alpha blocker (other than tamsulosin (Flomax) 0.4 mg once a day) such as doxazosin (Cardura), guanadrel (Hylorel), prazosin (Minipress), terazosin (Hytrin), alfuzosin (Uroxatral), and others.
Ingestion of tadalafil with any of the above medicines may cause very low blood pressure, and this can result in dizziness, fainting, stroke, or heart attack.
If you intend using tadalafil, tell your healthcare advisor if you have:
  • heart problems such as angina, heart failure, irregular heartbeats, or have had a heart attack;
  • low blood pressure or high blood pressure that is not controlled;
  • had a stroke;
  • liver problems;
  • kidney problems;
  • ever had blood cell problems such as sickle cell anemia, multiple myeloma, or leukemia;
  • a bleeding disorder;
  • a stomach ulcer;
  • retinitis pigmentosa (an inherited condition of the eye);
  • a physical deformity of the penis such as Peyronie's disease;
  • had an erection that lasted longer than 4 hours.
Your doctor or healthcare advisor may tell you not to take sildenafil, or you may require an adjustment of the dose, if you have any of these conditions.
The drug is not intended for and should not be taken by women. However, it is listed under the FDA’s pregnancy category B. In other words it should not harm an unborn foetus, but it is unknown if the drug passes into milk in the breast during pregnancy.
The over-65s are more susceptible to side-effects and you may be advised to take a lower dosage of the drug.

How must I take the drug?

Take it precisely as directed. If you do not understand these directions, ask your healthcare advisor to help you understand them.
Take each pill or part of the pill with a glass-full of water.
The drug is taken when required, with the effects lasting 36 hours or longer.
You can take Tadalafil whether or not you have eaten.
It should not be taken with excessive (more than 5 glasses) alcohol, which increases the danger of headache, dizziness, increased heart rate, or low blood pressure.
If you maintain an erection for more than four hours, seek emergency advice straight away. A prolonged erection can cause permanent harm to your penis. Do not engage in any more sex until the symptoms have gone and seek further medical advice if you experience (pain, tightness, discomfort, numbness, or tingling in the chest, arms, neck, or jaw) when having sex.
Some fruit juices can produce potentially harmful side-effects and discuss these with your healthcare advisor. Fort example, do not change your drinking habits of grapefruit juice before seeking medical advice.
Store the drug at normal room temperature, out of the damp or hot conditions.

What if I miss a dose?

The drug is taken as and when required, so you will not miss a dose.

Get emergency medical attention.
The symptoms of an overdose of this drug are not clearly known.

What are the potential side-effects of the drug?

Stop taking the drug and get emergency medical advice if you have any of the following:
  • an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
  • chest pain or an irregular heartbeat;
  • swelling of the ankles or legs;
  • shortness of breath;
  • prolonged or severe dizziness;
  • a prolonged (more than 4 hours) or painful erection; or
  • dizziness, nausea, or angina (pain, tightness, discomfort, numbness, or tingling in the chest, arms, neck, or jaw).
Some other, less serious, side effects might be experienced. In that case, keep taking the right dose of the drug and discuss with your healthcare advisor any of the following:
  • flushing;
  • mild dizziness;
  • headache;
  • nasal congestion;
  • diarrhea;
  • temporary abnormalities in vision; or
  • itching or a rash.
You may experience other side-effects. Discuss them with your healthcare advisor if they trouble or concern you.

What other drugs will affect tadalafil?

Do not take tadalafil if you have been prescribed any of the following:
  • a nitrate such as nitroglycerin (Nitrostat, Nitrolingual, Nitro-Dur, Nitro-Bid, Minitran, Deponit, Transderm-Nitro, others), isosorbide dinitrate (Dilatrate-SR, Isordil, Sorbitrate), isosorbide mononitrate (Imdur, ISMO, Monoket), and others;
  • nitrates are also found in some recreational drugs such as amyl nitrate or nitrite ("poppers"); or
  • an alpha blocker (other than tamsulosin (Flomax) 0.4 mg once a day) such as doxazosin (Cardura), guanadrel (Hylorel), prazosin (Minipress), terazosin (Hytrin), alfuzosin (Uroxatral), and others.
Before using the drug, tell your healthcare advisor if you are taking any of the following medicines:
  • any other drug used to treat impotence, such as alprostadil (Caverject, Muse, Edex) or yohimbine (Yocon, Yodoxin, others);
  • the antibiotic drugs clarithromycin (Biaxin), erythromycin (E-Mycin, Eryc, Ery-Tab, others), or troleandomycin (TAO);
  • an antifungal medication such as itraconazole (Sporanox) or ketoconazole (Nizoral);
  • the HIV medications amprenavir (Agenerase), delavirdine (Rescriptor), indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir), or saquinavir (Fortovase, Invirase);
  • cimetidine (Tagamet, Tagamet HB);
  • phenobarbital (Luminal);
  • carbamazepine (Tegretol) or phenytoin (Dilantin); or
  • rifampin (Rifadin, Rifamate) or rifabutin (Mycobutin).
If you have been prescribed any of the medication listed above, you might be advised against taking sildenafil, or may need to adjust the dose or arrange monitoring while you take it.
Other medicines may also react with sildenafil. Talk to your healthcare advisor before taking any other medication, including herbal products.

Where can I get more information?

Your healthcare advisor will have more information about the drug for you to discuss with him or her.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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